Clinical Research - Working with & for Patients to Improve Treatment Outcomes in Respiratory Diseases
Harnessing the power of the Gut-Lung Axis: Metabolic and Inflammatory Outcomes in Chronic Obstructive Pulmonary Disease.
The Translational Respiratory Immunology laboratory is committed to accelerating scientific discoveries into actionable treatments. For this reason we have partnered with renowned Respiratory Consultants at Tallaght University Hospital & St James's Hospital, the Cloonan Lab and advanced molecular biotechnology and high-performance computing providers to examine how the gut microbiome and metabolism affect clinical outcomes of people living with a respiratory disease or experiencing lung infections.
Help Us Breathe New Life into COPD Research!
Do you or a loved one live with Chronic Obstructive Pulmonary Disease (COPD)?
We are launching a new study to understand how the food we eat and the "good bacteria" in our bodies might hold the key to better lung health.
Why is this study important?
For the 500,000 people in Ireland living with COPD, flare-ups and chest infections can be life-altering. While current medicines help manage symptoms, they don’t offer a cure. We believe the secret to stronger lungs might lie in the crosstalk between nutrients and your microbiota (the microbes living in your gut and lungs). When these microbes are out of balance, they can hinder your immune system’s ability to fight off infections. Our research aims to find out exactly how specific nutrients can "reboot" these cells to reduce inflammation and prevent severe attacks.
What does the study involve?
We are looking for people living with COPD (non-smokers, ex-smokers and current smokers) and healthy volunteers (current/ex smokers and non-smokers) to help us compare how different body environments affect lung health.
Participation may include:
Providing a stool sample: To help us map the differences in gut bacteria.
A simple blood draw: So we can test how nutrients help your white blood cells fight infection.
Optional donation: For those already undergoing a planned bronchoscopy or if your doctor ordered a bone aspirate (bone marrow aspirate) as part of your clinical workup, you can choose to donate a small part of your clinical sample to help us study lung and bone marrow cells directly.
The Goal: Better Treatments
By understanding this link, we hope to develop new nutritional therapies and food supplements designed to improve lung function and quality of life for people with COPD and other inflammatory conditions.
Interested in taking part or learning more? Would you like me to create a "Frequently Asked Questions" section or a sign-up call-to-action button for the website?
Interest in taking part in the study or learning more about it?
Address
School of Medicine
Trinity Biomedical Sciences Institute
Second Floor
152-160 Pearse St, Dublin,
D02 R590, Ireland
Contact
Opening Hours
Mon - Fri
9:00 am – 5:00 pm
Saturday
Closed
Sunday
Closed